ABSTRACT
Background: Percutaneous edge-to-edge mitral valve repair (PMVR) use to manage patients with severe mitral regurgitation has been increasingly used over the past decade. Minimizing unnecessary hospital stays after elective procedures, including PMVR, has been an ongoing trend particularly since the COVID-19 pandemic to minimize patients’ exposure. Here we aim to evaluate trends and outcomes of early discharge post-PMVR. Methods: The Nationwide Readmissions Database 2016-2019 was queried for hospitalizations for PMVR. According to discharge day, hospitalizations were stratified into early discharge (<2 days from index admission) versus late discharge (≥ day 2) groups. Multivariable regression analyses were used to determine the association between discharge timing and 90-days readmission rates. Results The final analysis included 15,521 hospitalizations with 9,396 (60.5%) in the early discharge and 6,125(39.5%) in the late discharge groups with a mean age of 78.1±8.0 vs 78.5±8.7 years consecutively. Women made up 44% and 48% of the early vs late group. There was an increasing trend of early discharge post PMVR (Ptrend <0.001) (Figure). Early discharge was associated with lower odds of 90 days all-cause (adjusted odds ratio[aOR]:0.61;CI 0.55-0.68;P<0.01) and congestive heart failure readmission (aOR: 0.68: CI 0.60-0.77;P <0.01). Moreover, hospitalization costs were reduced by $6,584 (CI: 4,910- 8,257$). Conclusion. There has been an increased rate of early discharge post PMVR without an increased rate of readmission risk. Further randomized controlled studies are needed to validate these findings. [Formula presented]